The main bus station isn't the most impressive building in town, but it is well organized and conveniently located next to the ferry port and train station, which are all about ten minutes' walk to the old town. If you're planning a return trip to a domestic destination, make sure to check bus operators and travel times, as return tickets usually require you to travel with the same company on each leg of the trip. Also, if you happen to be traveling to the northern part of Croatia, check if the bus will be using the new highway or the curvy, car-sickness-inducing but aesthetically-pleasing old roads, which can affect the length of your trip. Information about prices and departure/arrival times is available 24 hours at the information desk. The international ticket office is open 06:00 - 21:30.

If you wish to travel to the Croatian capital Zagreb, the bus ride via freeway is 5 hours approximately. The first ride starts at 1:00am with buses leaving every hour thereafter. The last bus leaves at 23:59.

For those wishing to visit the Plitvice National Park there are four bus lines from Split. The first leaves at 08:30 and is followed by another at 12:00, 20:15 and 22:45.

Dubrovnik is at the very south of Croatia and is approximately 5 hours from Split by bus. The first bus leaves at 1:30 and the last at 17:15.

Makarska is almost half way to Dubrovnik and the first bus line towards this beautiful coastal town leaves at 1:30 with the last at 22:30. Bus lines leave almost every hour and the trip takes about 1 hour.

The first bus to Rijeka leaves at 05:00 and the trip takes about 7 hours, whilst the last bus leaves from Split to Rijeka at 21:30. There are eight bus lines towards Rijeka every day.