Virtually nothing has changed in this traditional drugstore since it first opened on Piazza San Giovanni in 1906 - the weather-beaten façade, the natural sea sponges hanging from the ceiling, and the aromatic mix of spices, soaps and other scents that overwhelms you upon entering all hail from a very different era that has almost ceased to exist in the 21st century. However, somewhat reassuringly many of the customers are from the younger generations, as natural products stocked here have once again come back in fashion, and will hopefully ensure that the legendary Toso continues on for another hundred years.