One of the most famous landmarks in Alfama is the Castelo de São Jorge, a castle that was built by the Moors in the 11th century and later expanded by the Portuguese. It offers stunning views of the city and the river, and is a popular tourist attraction. Other notable landmarks in the neighbourhood include the Sé Cathedral, the National Pantheon, and the Miradouro das Portas do Sol viewpoint.
Alfama is also home to a vibrant food and nightlife scene. Visitors can find many traditional restaurants and bars serving delicious Portuguese cuisine, as well as trendy cafes and nightclubs. The neighbourhood is particularly lively during the annual Santo António festival in June, which includes parades, music, and street parties.